Hormone
estradiol Audio
es·tra·di·ol [ es-truh-dahy-awl, -ol ]
Brand Names:
Alora; Bijuva; Climara; Climara Pro; Combipatch; Compudose; Delestrogen; Depo-estradiol; Divigel; Dotti; Elestrin; Estrace; Estring; Estrogel; Evamist; Femring; Gynodiol; Imvexxy; Lyllana; Menostar; Minivelle; Myfembree; Revalor; Synovex; Synovex C; Vagifem; Vivelle; Yuvafem
Effect:
Bone Formation Stimulation; Gonadotropin Releasing Hormone Alteration; Vaginal Function Alteration
May Prevent:
Osteoporosis, Postmenopausal
May Treat:
Breast Neoplasms; Hot Flashes; Hypogonadism; Menopause, Premature; Menorrhagia; Primary Ovarian Insufficiency; Prostatic Neoplasms
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to estradiol:
  • A form of the hormone estrogen.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position; estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • The most potent form of the naturally occurring steroid sex hormone in humans, produced by ovary, placenta, testis, and in small amount by adrenal cortex. Estradiol binds to a specific intracellular estrogen receptor located in female organs, breasts, hypothalamus and pituitary. The receptor-ligand complex promotes gene expression necessary for the maintenance of fertility and secondary sexual characteristics in females. In addition, estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. Estradiol, the principal intracellular human estrogen, is substantially more active at the cellular level than its metabolites, estrone and estriol.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • The primary form of the sex hormone estrogen produced by women.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.