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Gout and pseudogout
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Gout and pseudogout
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Gout pathophysiology
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Gout
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Related terms:
arthritis
infectious arthritis
psoriatic arthritis
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polymyalgia rheumatica
rheumatism
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Disease or Syndrome
gout Audio
gout [ gout ]
Subclass of:
Purine-Pyrimidine Metabolism, Inborn Errors; Crystal Arthropathies; Rheumatism; Arthritis
Also called:
Gouty arthritis
Definitions related to gout:
  • A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A condition marked by increased levels of uric acid in the blood, joints, and tissue. The buildup of uric acid in the joints and tissues causes arthritis and inflammation.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A form of arthritis that occurs when uric acid builds up in the joints; The big toe, knee, and ankle joints are most often affected.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • Gout is a common, painful form of arthritis. It causes swollen, red, hot and stiff joints. Gout happens when uric acid builds up in your body. Uric acid comes from the breakdown of substances called purines. Purines are in your body's tissues and in foods, such as liver, dried beans and peas, and anchovies. Normally, uric acid dissolves in the blood. It passes through the kidneys and out of the body in urine. But sometimes uric acid can build up and form needle-like crystals. When they form in your joints, it is very painful. The crystals can also cause kidney stones. Often, gout first attacks your big toe. It can also attack ankles, heels, knees, wrists, fingers, and elbows. At first, gout attacks usually get better in days. Eventually, attacks last longer and happen more often. You are more likely to get gout if you Are a man; Have family member with gout; Are overweight; Drink alcohol; Eat too many foods rich in purines. Gout can be hard to diagnose. Your doctor may take a sample of fluid from an inflamed joint to look for crystals. You can treat gout with medicines. Pseudogout has similar symptoms and is sometimes confused with gout. However, it is caused by calcium phosphate, not uric acid. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases
    MedlinePlus
    U.S. National Library of Medicine, 2021
  • Hereditary metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of uric acid calculi.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Recurrent attacks of acute inflammatory arthritis of a joint or set of joints caused by elevated levels of uric acid in the blood which crystallize and are deposited in joints, tendons, and surrounding tissues.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2021
  • Gout is a disorder caused by hyperuricemia (serum urate > 6.8 mg/dL [> 0.4 mmol/L]) that results in the precipitation of monosodium urate crystals in and around joints, most often causing recurrent acute or chronic arthritis. The initial attack (flare) of gout is usually monarticular and often involves the 1st metatarsophalangeal joint....
    Merck Manuals
    Merck & Co., Inc., 2020
  • Gout is a common and complex form of arthritis that can affect anyone. It's characterized by sudden, severe attacks of pain, swelling, redness and tenderness in the joints, often the joint at the base of the big toe.
    Mayo Clinic
    Mayo Foundation for Medical Education and Research
  • Gout is a syndrome characterized by: hyperuricemia and deposition of urate crystals causing attacks of acute inflammatory arthritis; tophi around the joints and possible joint destruction; renal glomerular, tubular, and interstitial disease; and uric acid urolithiasis. The disease most commonly affects the first toe (podagra), foot,...
    Epocrates
    Athenahealth, Inc., 2019
  • Gout, metabolic disorder characterized by recurrent acute attacks of severe inflammation in one or more of the joints of the extremities. Gout results from the deposition, in and around the joints, of uric acid salts, which are excessive throughout the body in persons with the disorder. Uric acid...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2020
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