Organic Chemical
hydroxamic acid
Subclass of:
Hydroxylamines; Hydroxy Acids
Definitions related to hydroxamic acids:
  • A class of weak acids with the general formula R-CONHOH.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A group of weak acids with the general chemical formula RC(=O)N(R')OH and antineoplastic and antimicrobial activities. Hydroxamic acids covalently bind to the zinc(II) ion in the active sites of matrix metalloproteinases (MMP), thereby inhibiting the action of MMPs, inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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