Antibiotic
nalidixic acid
Effect:
Decreased Protein Synthesis
May Treat:
Escherichia coli Infections; Klebsiella Infections; Proteus Infections; Salmonella Infections; Urinary Tract Infections
Definitions related to nalidixic acid:
  • A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A synthetic quinolone and antibacterial agent with urinary tract antiseptic activity. Nalidixic acid concentrates in the renal tubules and bladder and exerts its local antibacterial actions by interference of DNA gyrase activity, thereby inhibiting DNA synthesis during bacterial replication in a dose-dependent manner. Nalidixic acid is active against most gram-negative organisms that cause urinary tract infections.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.