Antibiotic
natamycin
Brand Names:
Natacyn
Effect:
Decreased Cell Membrane Integrity
May Treat:
Aspergillosis; Blastomycosis; Blepharitis; Candidiasis; Coccidioidomycosis; Conjunctivitis; Cryptococcosis; Eye Infections, Fungal; Histoplasmosis; Keratitis; Microsporidiosis; Sporotrichosis; Trichomonas Vaginitis
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to natamycin:
  • A polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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