Biologically Active Substance
neopterin
Subclass of:
Biopterin
Definitions related to neopterin:
  • A pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections. (From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of biopterin.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A pteridine that is a metabolite of guanine triphosphate (GTP) and a precursor for biopterin. Neopterin is released from interferon-gamma (IFNg) stimulated macrophages and dendritic cells (DCs); therefore, urine or serum levels may be used as a marker of immune system activation.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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