Hormone
nesiritide
Brand Names:
Natrecor
Effect:
Decreased Vascular Smooth Muscle Tone; Pulmonary Arterial Vasodilation; Systemic Arterial Vasodilation
May Treat:
Dyspnea, Paroxysmal
Definitions related to nesiritide:
  • A recombinant version of the cardiac neurohormone, human B-type natriuretic peptide (hBNP) produced by the ventricular myocardium. Nesiritide binds to natriuretic peptide receptors on vascular smooth muscle and endothelial cells, through which it triggers guanylate cyclase dependent signal transduction resulting in increase of intracellular concentrations of cGMP. This leads to smooth muscle cell relaxation causing arterial and venous dilatation.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • (natriuretic peptide, brain) A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MYOCARDIUM. It can cause NATRIURESIS; DIURESIS; VASODILATION; and inhibits secretion of RENIN and ALDOSTERONE. It improves heart function. It contains 32 AMINO ACIDS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
Try this search on: Farlex, Merriam-Webster, Oxford Dictionary, or Wordnik

This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.