(osteosarcoma, malignant) A malignant neoplasm usually arising from bone.

A cancer of the bone that usually affects the large bones of the arm or leg. It occurs most commonly in young people and affects more males than females.

A malignant bone tumor that usually develops during adolescence and usually affects the long bones including the tibia, femur, and humerus. The typical symptoms of osteosarcoma comprise bone pain, fracture, limitation of motion, and tenderness or swelling at the site of the tumor.

A malignant neoplasm of connective tissue origin that produces bone or osteoid.

A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)

A usually aggressive malignant bone-forming mesenchymal neoplasm, predominantly affecting adolescents and young adults. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus). Pain with or without a palpable mass is the most frequent clinical symptom. It may spread to other anatomic sites, particularly the lungs.

Malignant primary cancer of bone composed of a connective tissue stroma with evidence of malignant osteoid, bone and/or cartilage formation.

This article focuses on high-grade intramedullary osteosarcoma (often referred to simply as osteosarcoma), including its classic osteoblastic form and its fibroblastic and chondroblastic forms. Osteosarcoma is the most common malignant bone tumor.

Osteosarcoma is a type of bone cancer that begins in the cells that form bones. Osteosarcoma is most often found in the long bones - more often the legs, but sometimes the arms - but it can start in any bone. In very rare instances, it occurs in soft tissue outside the bone.

Osteosarcoma is the most common type of bone cancer. The average age at diagnosis is 15. Boys and girls have a similar incidence of this tumor until late adolescence, at which time boys are more commonly affected. In rare cases, osteosarcoma occurs in adults. Although osteosarcoma tends to occur in the larger bones, such as the shin...

The WHO defines osteosarcoma as a primary osseous malignant neoplasm composed of mesenchymal cells producing osteoid and immature bone, even if only in small amounts.

Osteosarcoma, most common bone cancer, primarily affecting the long bones, particularly those in the knee, hip, or shoulder regions. The cause of osteosarcoma is unknown, but genetic factors and radiation therapy may be involved in its development. Osteosarcoma occurs more often in males than in...