Cell or Molecular Dysfunction
oxidative stress Audio
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Subclass of:
Physiological Stress; Metabolism
Definitions related to oxidative stress:
  • A condition in which antioxidant levels are lower than normal. Antioxidant levels are usually measured in blood plasma.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products. The damage to biological tissues is caused by superoxide and other free radicals generated by many factors, including exposure to alcohol, medications, trauma, cold, toxins, and radiation or by antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; not synonymous with hypoxia or hyperoxia. Oxidative stress promotes a range of degenerative disorders, including cancer, diabetes, premature aging, Alzheimer's, and many others.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Damage to biological tissues caused by superoxide and other free radicals generated as a result of intoxication, antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; do not confuse with HYPOXIA or HYPEROXIA.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.