Congenital Abnormality
schizencephaly
Subclass of:
Malformations of Cortical Development, Group III
Definitions related to schizencephaly:
  • A rare developmental abnormality characterized by the presence of clefs in the cerebral hemispheres. The abnormality may involve one or both cerebral hemispheres. Signs and symptoms include developmental delays, mental retardation, paralysis, presence of a small head, and seizures.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Cortical malformations characterized by grey matter-lined cleft or cyst that extends from the EPENDYMA often to the PIA MATER outer surface. The grey matter that lines the cleft is often POLYMICROGYRIA. It is associated with developmental delay, motor disturbance and seizures.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • The presence of a cleft in the cerebral cortex unilaterally or bilaterally, usually located in the frontal area.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2021
  • Schizencephaly is a rare congenital (present from birth) brain malformation in which abnormal slits or clefts form in the cerebral hemispheres of the brain. The signs and symptoms of this condition may include developmental delay, seizures, and problems with brain-spinal cord communication. People with schizencephaly may also have an...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
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