Pharmacologic Substance
sevelamer
Brand Names:
RenaGel; Renvela
Effect:
Decreased Inorganic Ion Absorption; Inhibition Large Intestine Fluid/Electrolyte Absorption; Inhibition Small Intestine Fluid/Electrolyte Absorption
May Treat:
Hyperphosphatemia
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to sevelamer:
  • A non-absorbable polymeric amine and phosphate binding agent that can be used to prevent hyperphosphatemia. Upon oral administration, the amine groups in sevelamer become protonated in the intestines and bind to the dietary phosphate groups in the gastrointestinal (GI) tract, thereby preventing the absorption of phosphate and controlling phosphate plasma levels. In addition, sevelamer, as a phosphate binder, can be used to prevent the absorption of the radionuclide phosphorus P 32 (P-32).
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A polymeric amine that binds phosphate and is used to treat HYPERPHOSPHATEMIA in patients with kidney disease.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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