Pharmacologic Substance
sitagliptin phosphate
Effect:
Decreased Glucagon Secretion; Increased Insulin Secretion
May Treat:
Diabetes Mellitus, Type 2
More Information:
ChemID; DailyMed; DrugInfo; PDR
Definitions related to sitagliptin phosphate:
  • A pyrazine-derived DIPEPTIDYL-PEPTIDASE IV INHIBITOR and HYPOGLYCEMIC AGENT that increases the levels of the INCRETIN hormones GLUCAGON-LIKE PEPTIDE-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It is used in the treatment of TYPE 2 DIABETES.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • The phosphate salt form of sitagliptin, an orally available, competitive, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP-4) with hypoglycemic activity. Sitagliptin may cause an increased risk in the development of pancreatitis.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.