Pharmacologic Substance
sodium salicylate Audio
[ soh-dee-uhm suh-lis-uh-leyt, -lit, sal-uh-sil-eyt, sal-uh-sil- ]
Effect:
Increased Skin Keratinization
May Treat:
Acne Vulgaris; Dermatitis, Seborrheic; Keratosis, Seborrheic; Psoriasis; Scalp Dermatoses; Warts
More Information:
ChemID; DailyMed; DrugInfo; PDR
Definitions related to sodium salicylate:
  • A drug that is a type of nonsteroidal anti-inflammatory drug. Sodium salicylate may be tolerated by people who are sensitive to aspirin.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A non-steroidal anti-inflammatory agent that is less effective than equal doses of ASPIRIN in relieving pain and reducing fever. However, individuals who are hypersensitive to ASPIRIN may tolerate sodium salicylate. In general, this salicylate produces the same adverse reactions as ASPIRIN, but there is less occult gastrointestinal bleeding. (From AMA Drug Evaluations Annual, 1992, p120)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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