Pharmacologic Substance
staurosporine Audio
[ staw-roh-spor-een ]
Subclass of:
Indole Alkaloids; Carbazoles
Definitions related to staurosporine:
  • A cell permeable alkaloid isolated from Streptomyces staurosporeus exhibiting anti-cancer activity. Staurosporine is a potent, non-selective inhibitor of protein kinases, including protein kinase C. This agent induces apoptosis by an undetermined mechanism.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A drug that belongs to the family of drugs called alkaloids. It is being studied in the treatment of cancer.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • An indolocarbazole that is a potent PROTEIN KINASE C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Exhibits cytotoxic or antitumor properties; naturally derived from cultures of Streptomyces; inhibits protein kinase C.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.