Antibiotic
sulfamethoxazole Audio
sul·fa·meth·ox·a·zole [ suhl-fuh-meth-ok-suh-zohl ]
Brand Names:
Bactrim; Sulfatrim
Effect:
Cellular Synthetic Activity Alteration; Decreased Folic Acid Modification
May Treat:
Bronchitis, Chronic; Chlamydiaceae Infections; Enterobacteriaceae Infections; Nocardia Infections; Otitis Media; Pneumonia, Pneumocystis; Toxoplasmosis; Urinary Tract Infections
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to sulfamethoxazole:
  • A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A sulfonamide bacteriostatic antibiotic that is most commonly used in combination with trimethoprim as the drug Bactrim. Sulfamethoxazole competitively inhibits dihydropteroate synthase preventing the formation of dihydropteroic acid, a precursor of folic acid which is required for bacterial growth.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Sulfonamide bacteriostatic antibacterial agent.
    CRISP Thesaurus
    National Institutes of Health, 2006
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