Pharmacologic Substance
temazepam
Brand Names:
Restoril
Effect:
Increased Central Nervous System GABA Activity
May Treat:
Depressive Disorder; Panic Disorder; Sleep Initiation and Maintenance Disorders
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to temazepam:
  • A benzodiazepine derivative with antidepressant, sedative, hypnotic and anticonvulsant properties. Temazepam potentiates the inhibitory activities of gamma-aminobutyric acid (GABA) by binding to the GABA receptor, located in the limbic, neocortical and mesencephalic reticular system. This increases the frequency of chloride channel opening events, allowing the flow of chloride ions into the neuron leading to membrane hyperpolarization and decreases neuronal excitability.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A benzodiazepine that acts as a GAMMA-AMINOBUTYRIC ACID modulator and anti-anxiety agent.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.