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Disease or Syndrome
toxic shock syndrome Audio
tox·ic shock syn·drome
Definitions related to toxic shock syndrome:
  • A rare acute life-threatening systemic bacterial noncontagious illness caused by any of several related staphylococcal exotoxins. It is characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Profoundly reduced blood flow that results in impaired tissue perfusion and possible end organ damage resulting from an exotoxin released from certain bacteria, most often Staphylococcus aureus, or Streptococcus pyogenes.
    NICHD Pediatric Terminology
    U.S. National Cancer Institute, 2021
  • Syndrome characterized by high fever, vomiting, diarrhea, confusion, and skin rash; almost all cases have been related to an infection with toxin-producing Staphylococcus aureus.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Toxic shock syndrome is caused by staphylococcal or streptococcal exotoxins. Manifestations include high fever, hypotension, diffuse erythematous rash, and multiple organ dysfunction, which may rapidly progress to severe and intractable shock. Diagnosis is made clinically and by isolating the organism. Treatment includes antibiotics,...
    Merck Manuals
    Merck & Co., Inc., 2020
  • Toxic shock syndrome (TSS) is a toxin-mediated acute life-threatening illness, usually precipitated by infection with either Staphylococcus aureus or group A Streptococcus (GAS), also called Streptococcus pyogenes. It is characterized by high fever, rash, hypotension, multiorgan failure (involving at least 3 or more organ systems), and...
    Medscape
    WebMD, 2019
  • Toxic shock syndrome is a rare, life-threatening complication of certain types of bacterial infections. Often toxic shock syndrome results from toxins produced by Staphylococcus aureus (staph) bacteria, but the condition may also be caused by toxins produced by group A streptococcus (strep) bacteria.
    Mayo Clinic
    Mayo Foundation for Medical Education and Research
  • Toxic shock syndrome (TSS) is an exotoxin-mediated illness caused by bacterial infection. Organisms commonly responsible include group A streptococcus ( Streptococcus pyogenes ), or methicillin-sensitive (MSSA) or methicillin-resistant (MRSA) Staphylococcus aureus .
    Epocrates
    Athenahealth, Inc., 2019
  • Toxic shock syndrome, inflammatory disease characterized by high fever, headache, diarrhea, vomiting, irritability, sore throat, and rash. Abdominal tenderness, severe hypotension, shock, respiratory distress, and renal failure sometimes develop. The condition is caused by an exotoxin--that is, a...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2020
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