Pharmacologic Substance
vatalanib Audio
[ va-tah-la-nib ]
Definitions related to vatalanib:
  • A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called protein tyrosine kinase inhibitors and VEGF receptor kinase inhibitors.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • An orally bioavailable anilinophthalazine with potential antineoplastic activity. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis. This agent also binds to and inhibits related receptor tyrosine kinases, including platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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