Pharmacologic Substance
voriconazole Audio
[ vor-ih-kah-nuh-zole ]
Brand Names:
Vfend
Effect:
Decreased Cell Membrane Integrity; Decreased Cell Membrane Synthesis & Repair
May Treat:
Aspergillosis; Candidiasis; Fusariosis
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to voriconazole:
  • A drug that treats infections caused by fungi.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 CYP3A.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.