Antibiotic
neomycin
ne·o·my·cin [ nee-oh-mahy-sin ]
Brand Names:
Baclezene; Casporyn HC; Coly Mycin S; Cortisporin; Cortisporin Ointment; Cortisporin-TC; Cuadriderma; Dermalone; Lanabiotic; Maxitrol; Mycitracin Plus Pain Reliever; Neo-Polycin; Neo-Polycin HC; Neo-Predef; Neo-Synalar; Neovet; Oticin HC; Poly-Dex; ProCoMycin; Spectrocin Plus; Tresaderm; Tri Biozene; Triplicin; Vetropolycin; Vetropolycin HC; Vitacilina
Effect:
Decreased Protein Synthesis
May Prevent:
Bacterial Infections
May Treat:
Escherichia coli Infections;
Hepatic Encephalopathy;
Skin Diseases, Bacterial
More Information:
Definitions related to neomycin:
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A broad spectrum aminoglycoside antibiotic derived from Streptomyces fradiae with antibacterial activity. Neomycin is an antibiotic complex consisting of 3 components: the two isomeric components B and C are the active components, and neomycin A is the minor component. Neomycin irreversibly binds to the 16S rRNA and S12 protein of the bacterial 30S ribosomal subunit. As a result, this agent interferes with the assembly of initiation complex between mRNA and the bacterial ribosome, thereby inhibiting the initiation of protein synthesis. In addition, neomycin induces misreading of the mRNA template and causes translational frameshift, thereby results in premature termination. This eventually leads to bacterial cell death.NCI ThesaurusU.S. National Cancer Institute, 2021
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Aminoglycoside antibiotic complex produced by Streptomyces fradiae. It is composed of neomycins A, B, and C, and acts by inhibiting translation during protein synthesis.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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