Pharmacologic Substance
Mebendazole
A synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake. This results in a depletion of glycogen...
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Brand Names:
Emverm; Vermox
Effect:
Decreased Glucose Transport into Cells
May Treat:
Group:
Benzimidazoles; Carbamates
Mechanism:
Receptor Interactions; Tubulin Interactions
More Information:
Medscape
Emverm, Vermox (mebendazole) dosing, indications, interactions, adverse effects, and more.
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Mebendazole is used to treat several types of worm infections. Mebendazole (Vermox) is used to treat roundworm and whipworm infections.
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Feb 1, 2022 ... Mebendazole is used to treat infections caused by worms. It works by keeping the worm from absorbing sugar (glucose), so that the worm loses ...
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Mar 23, 2020 ... Mebendazole works by preventing the worms from absorbing sugars which they need to survive. This kills the worm within a few days.
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Jul 29, 2021 ... Mebendazole is an anthelmintic (an-thel-MIN-tik) or anti-worm medication. It prevents newly hatched insect larvae (worms) from growing or ...
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Mebendazole is a (synthetic) broad-spectrum anthelmintic. The principal mode of action for Mebendazole is by its inhibitory effect on tubulin polymerization ...
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Mar 28, 2017 ... Mebendazole showed antifungal activity against phagocytized C. neoformans, affected cryptococcal biofilms profoundly and caused marked ...
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Apr 20, 2020 ... Mebendazole is poorly excreted into breastmilk and poorly absorbed orally. Reports on the use of mebendazole during breastfeeding have found ...
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The purpose of this study is to find the highest dose of mebendazole (MBZ) that can be safely given to people with malignant brain tumors in combination ...
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Apr 5, 2017 ... Mebendazole has been shown to inhibit microtubule formation, but it is not known whether its potency against tumor cells is mediated by this ...
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Recently, it was discovered that mebendazole may be effective in treating cancer as well, in particular brain tumors. Studies using both cell cultures and mouse ...