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Antibiotic
Neomycin
A broad spectrum aminoglycoside antibiotic derived from Streptomyces fradiae with antibacterial activity. Neomycin is an antibiotic complex consisting of 3 components: the two isomeric components B and C are the active components, and neomycin A is the minor component. Neomycin irreversibly binds... NCI Thesaurus more
A broad spectrum aminoglycoside antibiotic derived from Streptomyces fradiae with antibacterial activity. Neomycin is an antibiotic complex consisting of 3 components: the two isomeric components B and C are the active components, and neomycin A is the minor component. Neomycin irreversibly binds to the 16S rRNA and S12 protein of the bacterial 30S ribosomal subunit. As a result, this agent interferes with the assembly of initiation complex between mRNA and the bacterial ribosome, thereby inhibiting the initiation of protein synthesis. In addition, neomycin induces misreading of the mRNA template and causes translational frameshift, thereby results in premature termination. This eventually leads to bacterial cell death. NCI Thesaurus
Brand Names:
Baclezene; Casporyn HC; Coly Mycin S; Cortisporin; Cortisporin Ointment; Cortisporin-TC; Cuadriderma; Dermalone; Lanabiotic; Maxitrol; Mycitracin Plus Pain Reliever; Neo-Polycin; Neo-Polycin HC; Neo-Predef; Neo-Synalar; Neovet; Oticin HC; Poly-Dex; ProCoMycin; Spectrocin Plus; Tresaderm; Tri Biozene; Triplicin; Vetropolycin; Vetropolycin HC; Vitacilina
Effect:
Decreased Protein Synthesis
May Prevent:
Bacterial Infections
May Treat:
Escherichia coli Infections; Hepatic Encephalopathy; Skin Diseases, Bacterial
Group:
Aminoglycosides
Mechanism:
Protein Synthesis Inhibitors
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Always consult a medical professional for advice (Terms) Use Notice Feedback Sources
Images:
  • Neomycin image from Wikimedia
  • Neomycin image from Wikimedia
  • Wikimedia
Definitions:
Neomycin
NLM Medical Subject Headings
Aminoglycoside antibiotic complex produced by Streptomyces fradiae. It is composed of neomycins A, B, and C, and acts by inhibiting translation during protein synthesis.
Neomycin
NLM Medical Subject Headings
Aminoglycoside antibiotic complex produced by Streptomyces fradiae. It is composed of neomycins A, B, and C, and acts by inhibiting translation during protein synthesis.
Related topics:
Anthracyclines
Butirosin Sulfate
Gentamicins
Hygromycin B
Kanamycin
Metrizamide
more...
Related terms:
Anthracyclines
Butirosin Sulfate
Gentamicins
Hygromycin B
Kanamycin
Metrizamide
Puromycin
Spectinomycin
Streptomycin
Streptothricins
Streptozocin
Viewing results 1 - 10 of 9,800,000 (0.24 seconds)
  • Neomycin Topical: MedlinePlus Drug Information
    Neomycin, an antibiotic, is used to prevent or treat skin infections caused by bacteria. It is not effective against fungal or viral infections.
    medlineplus.gov/druginfo/meds/a682274.html
  • Neomycin: Uses, Interactions, Mechanism of Action | DrugBank Online
    Neomycin is an aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
    go.drugbank.com/drugs/DB00994
  • Neomycin, Polymyxin, and Bacitracin Topical: MedlinePlus Drug ...
    Neomycin, polymyxin, and bacitracin combination is used to prevent minor skin injuries such as cuts, scrapes, and burns from becoming infected.
    medlineplus.gov/druginfo/meds/a601098.html
  • Neomycin Uses, Side Effects & Warnings - Drugs.com
    Jun 25, 2021 ... Neomycin is an antibiotic that is used to prevent bacterial infection in the intestines. Neomycin is also used to reduce the symptoms of ...
    drugs.com/mtm/neomycin.html
  • Neomycin (Oral Route) Proper Use - Mayo Clinic
    Feb 1, 2022 ... Oral neomycin is used to help lessen the symptoms of hepatic coma, a complication of liver disease. In addition, it may be used with another ...
    mayoclinic.org/drugs.../neomycin-oral-route/.../drg-20065027? ...
  • Neomycin Oral: Uses, Side Effects, Interactions, Pictures, Warnings ...
    Neomycin belongs to a class of drugs known as aminoglycoside antibiotics. It works by stopping the growth of bacteria in the intestines.Neomycin may also be ...
    webmd.com/drugs/2/drug-8047/neomycin-oral/details
  • Neomycin (Oral Route) Side Effects - Mayo Clinic
    Feb 1, 2022 ... Any loss of hearing · clumsiness · diarrhea · difficulty in breathing · dizziness · drowsiness · greatly decreased frequency of urination or amount of ...
    mayoclinic.org/drugs-supplements/neomycin.../drg-20065027
  • In Vitro Activity of Neomycin, Streptomycin, Paromomycin ... - Frontiers
    Nov 17, 2017 ... Antimicrobial Susceptibility Testing. MICs of aminoglycosides (amikacin, gentamicin, tobramycin, apramycin, neomycin, paromomycin, and ...
    frontiersin.org/articles/10.3389/fmicb.2017.02275/full
  • COMBINED BACITRACIN-NEOMYCIN OINTMENT IN TREATMENT ...
    However, the hepatotoxic and ototoxic properties of neomycin preclude its systemic adminstration. Some patients with hemolytic Streptococcus and B. pyocyaneus ( ...
    jamanetwork.com/journals/jamadermatology/fullarticle/523917
  • Definition of neomycin - NCI Drug Dictionary - National Cancer ...
    neomycin. A broad spectrum aminoglycoside antibiotic derived from Streptomyces fradiae with antibacterial activity. Neomycin is an antibiotic complex consisting ...
    cancer.gov/publications/dictionaries/cancer-drug/.../neomycin
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