Enzyme
Neuraminidase
An enzyme that catalyzes the hydrolysis of alpha-2,3, alpha-2,6-, and alpha-2,8-glycosidic linkages (at a decreasing rate, respectively) of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid, and synthetic substrate. (From Enzyme Nomenclature, 1992)
Viewing results
1 - 10 of 2,420,000 (0.22 seconds)
-
Jan 29, 2019 ... Although the influenza A virus surface glycoprotein neuraminidase (NA) has been studied mainly in the context of its role in viral release ...
-
Influenza virus neuraminidase (NA) plays an essential role in release and spread of progeny virions, following the intracellular viral replication cycle.
-
Feb 23, 2000 ... ContextPrevious studies have shown oseltamivir, a neuraminidase inhibitor, to be effective in preventing influenza and treating experimental ...
-
Aug 14, 2017 ... The neuraminidase inhibitors oseltamivir and zanamivir, currently authorised in the European Union/European Economic Area for treatment and ...
-
Sep 29, 2005 ... The neuraminidase inhibitors zanamivir and oseltamivir interfere with the release of progeny influenza virus from infected host cells, a process ...
-
neuraminidase, also called sialidase, any of a group of enzymes that cleave sialic acid, a carbohydrate occurring on the surfaces of cells in humans and ...
-
Apr 10, 2014 ... Neuraminidase inhibitors (NIs) are stockpiled and recommended by public health agencies for treating and preventing seasonal and pandemic ...
-
May 12, 2017 ... Influenza A viruses generally mediate binding to cell surface sialic acid receptors via the hemagglutinin (HA) glycoprotein, with the ...
-
Dec 17, 1999 ... Neuraminidase inhibitors are a new class of antiviral drugs that inhibit influenza A and B viruses. Zanamivir is approved for treatment of ...
-
Apr 5, 2022 ... Influenza virus neuraminidase (NA) is a major antiviral drug target and has recently reemerged as a key target of antibody-mediated ...