Pharmacologic Substance
Nitroarginine
An amino acid derivative and nitric oxide synthase (NOS) inhibitor with potential antineoplastic and antiangiogenic activities. Upon administration, NG-nitro-L-arginine inhibits the enzyme nitric oxide synthase, thereby preventing the formation of nitric oxide (NO). By preventing NO generation, the...
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Nitroarginine is being studied in the treatment of cancer and other conditions. In cancer, it may stop the growth of tumor cells by blocking certain ...
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Jun 13, 2005 ... An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for ...
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Aug 24, 1993 ... Selective inhibition of constitutive nitric oxide synthase by L-NG-nitroarginine. Eric S. Furfine; ,; Marilyn F. Harmon; ,; Jerilin E. Paith ...
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Aug 3, 2017 ... Tadalafil Improves L-NG-Nitroarginine Methyl Ester-Induced Preeclampsia With Fetal Growth Restriction-Like Symptoms in Pregnant Mice.
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L-NG-Nitroarginine (NA) inhibited both the L-arginine oxidation and the L-arginine-independent NADPH oxidation reactions catalyzed by the ...
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NG-nitro-L-arginine is an amino acid derivative and nitric oxide synthase (NOS) inhibitor with potential antineoplastic and antiangiogenic activities.
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1. The effects of L-NG-nitroarginine (L-NOARG) and L-NG-nitroarginine methyl ester (L-NAME) on vasodilatation induced by ATP, substance P, ...
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Published: 01 April 1998. L-Nitroarginine (LNA) Paradoxically Induces Nitric Oxide Synthases in the Newborn Brain and Cerebral Microvessels ♢ 345.
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Nitroarginine, an inhibitor of nitric oxide synthetase, attenuates ammonia toxicity and ammonia-induced alterations in brain metabolism · Authors · Affiliation.
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NG -monomethyl- l-arginine (l-NMMA), and NG-nitroarginine methyl ester (l-NAME), which are substituted at a guanidino nitrogen, are widely ested. (l-NAME) has ...