Immunologic Factor
Oprelvekin
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin 11 (IL-11). Secreted by bone marrow stromal cells and a number of mesenchymal cells, IL-11 binds to and activates its cell-surface receptor, promoting primary and secondary immune...
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Brand Names:
Neumega
Effect:
Increased Megakaryocte Cell Production; Increased Thromboxane Production
May Prevent:
Mechanism:
Thrombopoietin Receptor Agonists
Medscape
Neumega, Interleukin 11 (oprelvekin) dosing, indications, interactions, adverse effects, and more.
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Feb 1, 2022 ... The side effects listed below include only those that might be caused by oprelvekin. To find out about other side effects that may be caused ...
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Jun 13, 2005 ... Oprelvekin is a form of recombinant interleukin-11 used to stimulate production of megakaryocytes and platelets in patients with or at risk ...
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Medscape - Indication-specific dosing for Neumega, Interleukin 11 (oprelvekin), frequency-based adverse effects, comprehensive interactions, ...
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A drug used to increase the number of blood cells, especially platelets, in some cancer patients receiving chemotherapy. Oprelvekin is a form of interleukin-11 ...
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NOTE: Oprelvekin has been designated an orphan drug by the FDA for this indication. Subcutaneous dosage. Adults and Adolescents†. The recommended dose is 50 mcg ...
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Jun 8, 2016 ... Oprelvekin is a recombinant form of human interleukin 11, a cytokine that stimulates proliferation and maturation of bone marrow stem cells ...
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(oprelvekin). Rx only. BOXED WARNING. Allergic Reactions Including Anaphylaxis. Neumega has caused allergic or hypersensitivity reactions, ...
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Oprelvekin (Neumega®, IL-11) is a colony stimulating growth factor used in supportive care treatment to increase production and maturation of platelets.
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Oprelvekin is indicated for the prevention of severe thrombocytopenia and the reduction of platelet transfusion requirements following myelosuppressive ...
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Pediatric Patient Graphics. Showing results for Oprelvekin (Recombinant human interleukin-11) united states not available patient drug information.