Antibiotic
Puromycin
An aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. Acting as an analog of the 3' terminal end of aminoacyl-tRNA, puromycin incorporates itself into a growing polypeptide chain and causes its premature termination, thereby inhibiting protein synthesis. This agent has...
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Dec 12, 2011 ... Other methods to assay translation rely on the incorporation of puromycin (puro) into nascent proteins. Puro (Fig. 1A) is an aminonucleoside ...
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Aug 26, 2020 ... Puromycin is a tyrosyl-tRNA mimic that blocks translation by labeling and releasing elongating polypeptide chains from translating ribosomes ...
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May 1, 2009 ... Taken together we propose that puromycin vectors may elicit an unexpected misfolded protein response, associated with the formation of ...
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Puromycin is a tyrosyl-tRNA mimic that blocks translation by labeling and releasing elongating polypeptide chains from translating ribosomes.
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Nov 10, 2015 ... A selectable murine transgenic embryonic stem cell (ESC) line (Sim1-Puro) was generated by recombineering. The expression of the puromycin ...
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Apr 13, 2016 ... Here, we describe a chemical genetic method that involves orthogonal enzyme-mediated incorporation of a clickable puromycin analogue into ...
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Puromycin (Stylomycin) * is an antibiotic obtained from a species of actinomycete, Streptomyces albo-niger.† In addition to its inhibitory action on some ...
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Jan 18, 2018 ... In SUnSET, a cell culture is pulsed with puromycin during which the puromycin is incorporated into the elongating peptides; this process ...
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Oct 3, 2016 ... Puromycin (6, PURO; Figure 2) is an aminonucleoside antibiotic that inhibits protein synthesis in both bacteria and eukaryotes by mimicking ...
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Puromycin · Puromycin is an aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. · Puromycin is an aminonucleoside antibiotic, derived ...