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Antibiotic
Rifampin
A semisynthetic derivative of rifamycin with broad antibacterial activity. Rifampin inhibits DNA-dependent RNA polymerase in susceptible bacteria and is often used in combination with other antibiotics for various infections including tuberculosis. NCI Thesaurus
A semisynthetic derivative of rifamycin with broad antibacterial activity. Rifampin inhibits DNA-dependent RNA polymerase in susceptible bacteria and is often used in combination with other antibiotics for various infections including tuberculosis. NCI Thesaurus
Brand Names:
Rifadin; Rifamate; Rifater
Effect:
Decreased RNA Replication; Decreased Transcription to RNA
May Prevent:
Meningitis, Meningococcal; Tuberculosis
May Treat:
AIDS-Related Opportunistic Infections; Brucellosis; Haemophilus Infections; Legionnaires' Disease; Leprosy; Meningitis, Bacterial; Staphylococcal Infections; Tuberculosis
Group:
Rifamycins
Mechanism:
Nucleic Acid Synthesis Inhibitors
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Always consult a medical professional for advice (Terms) Use Notice Feedback Sources
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rifampin
Medscape
Rifadin, Rimactane (rifampin) dosing, indications, interactions, adverse effects, and more.
Images:
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  • Rifampin image from Wikimedia
  • Wikimedia
Definitions:
rifampin
NCI Dictionary of Cancer Terms
A drug used in the treatment of infections caused by bacteria. It belongs to the family of drugs called antibiotics.
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rifampin
NCI Dictionary of Cancer Terms
A drug used in the treatment of infections caused by bacteria. It belongs to the family of drugs called antibiotics.
Rifampin
NLM Medical Subject Headings
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)
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