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Antibiotic
Streptomycin
An aminoglycoside antibiotic derived from Streptomyces griseus with antibacterial activity. Streptomycin irreversibly binds to the 16S rRNA and S12 protein within the bacterial 30S ribosomal subunit. As a result, this agent interferes with the assembly of initiation complex between mRNA and the... NCI Thesaurus more
An aminoglycoside antibiotic derived from Streptomyces griseus with antibacterial activity. Streptomycin irreversibly binds to the 16S rRNA and S12 protein within the bacterial 30S ribosomal subunit. As a result, this agent interferes with the assembly of initiation complex between mRNA and the bacterial ribosome, thereby inhibiting the initiation of protein synthesis. In addition, streptomycin induces misreading of the mRNA template and causes translational frameshift, thereby results in premature termination. This eventually leads to bacterial cell death. NCI Thesaurus
Effect:
Decreased Protein Synthesis
May Treat:
Brucellosis; Chancroid; Endocarditis, Bacterial; Escherichia coli Infections; Granuloma Inguinale; Klebsiella Infections; Mycobacterium Infections; Plague; Proteus Infections; Streptococcal Infections; Tularemia; Urinary Tract Infections
Group:
Aminoglycosides
Mechanism:
Protein Synthesis Inhibitors
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Always consult a medical professional for advice (Terms) Use Notice Feedback Sources
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streptomycin
Medscape
(streptomycin) dosing, indications, interactions, adverse effects, and more.
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Streptomycin
Encyclopedia Britannica
Streptomycin, antibiotic synthesized by the soil organism Streptomyces griseus. Streptomycin was discovered by American biochemists Selman Waksman, Albert Schatz, and Elizabeth Bugie in 1943....
Images:
  • Streptomycin image from Wikimedia
  • Streptomycin image from Wikimedia
Definitions:
Streptomycin
NLM Medical Subject Headings
An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.
more...
Streptomycin
NLM Medical Subject Headings
An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.
streptomycin
CRISP Thesaurus
First of the aminoglycoside antibiotics to be isolated; derived from Streptomyces griseus.
Related topics:
Anthracyclines
Butirosin Sulfate
Gentamicins
Hygromycin B
Kanamycin
Metrizamide
more...
Related terms:
Anthracyclines
Butirosin Sulfate
Gentamicins
Hygromycin B
Kanamycin
Metrizamide
Neomycin
Puromycin
Spectinomycin
Streptothricins
Streptozocin
Viewing results 1 - 10 of 43,800,000 (0.28 seconds)
  • Streptomycin | C21H39N7O12 - PubChem
    Streptomycin is an aminoglycoside antibiotic derived from Streptomyces griseus with antibacterial activity. Streptomycin irreversibly binds to the 16S rRNA and ...
    pubchem.ncbi.nlm.nih.gov/compound/Streptomycin
  • Streptomycin: Uses, Interactions, Mechanism of Action | DrugBank ...
    Jun 13, 2005 ... Streptomycin is an aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis ...
    go.drugbank.com/drugs/DB01082
  • (streptomycin) dosing, indications, interactions, adverse effects, and ...
    Streptomycin belongs to a class of drugs known as aminoglycoside antibiotics. It works by killing the organisms that cause the infection.This drug may also be ...
    reference.medscape.com/drug/streptomycin-342682
  • Heterogeneous Streptomycin Resistance Level Among ... - Frontiers
    Jun 11, 2021 ... Streptomycin resistance was the most frequent resistance in the cohort accounting for 82.7% (n = 67) of the resistant Mycobacterium tuberculosis ...
    frontiersin.org/articles/10.3389/fmicb.2021.659545/full
  • Doxycycline plus streptomycin versus ciprofloxacin plus rifampicin in ...
    Apr 11, 2006 ... The combination of doxycycline with streptomycin is accepted to be the most effective regimen in spinal brucellosis [1]. However, therapeutic ...
    bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-6-72
  • STREPTOMYCIN FOR URINARY TRACT INFECTIONS | JAMA ...
    Streptomycin has been shown to be effective in vitro1 against various gram-negative bacilli frequently responsible for urinary infections which prove ...
    jamanetwork.com/journals/jama/fullarticle/291952
  • Interactive diabetes case 15: A 74-year-old patient with type 2 ...
    Jan 26, 2022 ... Incorrect.Increases in the doses of insulin are necessary for the management of the patient's uncontrolled diabetes but not sufficient at ...
    uptodate.com/.../interactive-diabetes-case-15-a-74-year-old- patient-with-type-2-diabetes-and-recurrent-hyperkalemia-c1
  • STREPTOMYCIN IN TREATMENT OF WHOOPING COUGH | JAMA ...
    It has been shown that Hemophilus pertussis, the etiologic agent of whooping cough, is sensitive to streptomycin in concentrations of from 1 to 3 micrograms in ...
    jamanetwork.com/journals/jamapediatrics/fullarticle/1180884
  • Streptomycin - Drugs and Lactation Database (LactMed) - NCBI ...
    Sep 21, 2020 ... Similar to other aminoglycoside antibiotics, streptomycin is poorly excreted into breastmilk. Newborn infants apparently absorb small ...
    ncbi.nlm.nih.gov/books/NBK501102/
  • Streptomycin (Intramuscular Route) Before Using - Mayo Clinic
    Feb 1, 2022 ... No information is available on the relationship of age to the effects of streptomycin injection in geriatric patients. However, elderly patients ...
    mayoclinic.org/drugs.../streptomycin...route/.../drg-20074514
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