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Pharmacologic Substance
Valganciclovir
A synthetic prodrug of ganciclovir, a nucleoside analogue of 2'-deoxyguanosine, with antiviral activity. After phosphorylation, valganciclovir is incorporated into DNA, resulting in inhibition of viral DNA polymerase, viral DNA synthesis, and viral replication. (NCI04) NCI Thesaurus
A synthetic prodrug of ganciclovir, a nucleoside analogue of 2'-deoxyguanosine, with antiviral activity. After phosphorylation, valganciclovir is incorporated into DNA, resulting in inhibition of viral DNA polymerase, viral DNA synthesis, and viral replication. (NCI04) NCI Thesaurus
Brand Names:
Valcyte
Effect:
Decreased DNA Integrity; Decreased DNA Replication
May Prevent:
Cytomegalovirus Infections
May Treat:
AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis
Group:
Ganciclovir
Mechanism:
Nucleic Acid Synthesis Inhibitors
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Always consult a medical professional for advice (Terms) Use Notice Feedback Sources
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valganciclovir
Medscape
Valcyte (valganciclovir) dosing, indications, interactions, adverse effects, and more.
Images:
  • Valganciclovir image from Wikimedia
  • Valganciclovir image from Wikimedia
Definitions:
Valganciclovir
NLM Medical Subject Headings
A ganciclovir prodrug and antiviral agent that is used to treat CYTOMEGALOVIRUS RETINITIS in patients with AIDS, and for the prevention of CYTOMEGALOVIRUS INFECTIONS in organ transplant recipients who have received an organ from a CMV-positive donor.
more...
Valganciclovir
NLM Medical Subject Headings
A ganciclovir prodrug and antiviral agent that is used to treat CYTOMEGALOVIRUS RETINITIS in patients with AIDS, and for the prevention of CYTOMEGALOVIRUS INFECTIONS in organ transplant recipients who have received an organ from a CMV-positive donor.
valganciclovir
NCI Dictionary of Cancer Terms
An antiviral agent that is being studied as a treatment for AIDS-related cytomegalovirus. It is changed in the body to ganciclovir.
Viewing results 1 - 10 of 687,000 (0.27 seconds)
  • Valganciclovir: MedlinePlus Drug Information
    Oct 15, 2018 ... Valganciclovir may lower the number of red blood cells, white blood cells, and platelets in your body, causing serious and life-threatening ...
    medlineplus.gov/druginfo/meds/a605021.html
  • Valganciclovir for Symptomatic Congenital Cytomegalovirus ...
    Mar 5, 2015 ... The treatment of symptomatic congenital cytomegalovirus (CMV) disease with intravenous ganciclovir for 6 weeks has been shown to improve ...
    nejm.org/doi/full/10.1056/NEJMoa1404599
  • Valganciclovir (Oral Route) Side Effects - Mayo Clinic
    Mar 1, 2022 ... Valganciclovir is an antiviral. It is used to treat infections caused by viruses. This medicine is also used to prevent CMV disease in ...
    mayoclinic.org/drugs.../valganciclovir-oral.../drg-20066642?p...
  • Valcyte (valganciclovir) dosing, indications, interactions, adverse ...
    Valganciclovir works by slowing the growth of the CMV virus. It helps prevent the spread of infection to other areas of the body.Valganciclovir is also used to ...
    reference.medscape.com/drug/valcyte-valganciclovir-342632
  • Valganciclovir: Uses, Interactions, Mechanism of Action | DrugBank ...
    Valganciclovir is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ...
    go.drugbank.com/drugs/DB01610
  • Valganciclovir Reduces T Cell Activation in HIV-infected Individuals ...
    Thirty antiretroviral therapy–treated HIV-infected CMV-seropositive participants with CD4 counts <350 cells/mm3 were randomized to receive valganciclovir ...
    ncbi.nlm.nih.gov/pmc/articles/PMC3080892/
  • Definition of valganciclovir - NCI Dictionary of Cancer Terms - NCI
    NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.
    cancer.gov/publications/dictionaries/cancer.../valganciclovir
  • Valganciclovir for Cytomegalovirus Prevention in Solid Organ ...
    May 13, 2009 ... For every 24 patients who receive valganciclovir prophylaxis, one more will develop neutropenia compared to other therapies. The risk of late- ...
    ncbi.nlm.nih.gov/pmc/articles/PMC2677673/
  • Valganciclovir: Pediatric Medication | Memorial Sloan Kettering ...
    What is this drug used for? · It is used to treat cytomegalovirus (CMV) infection of the eyes in people with immune system problems. · It is used to prevent ...
    mskcc.org/cancer-care/patient-education/valganciclovir
  • Pharmacokinetic and Pharmacodynamic Assessment of Oral ...
    Pharmacokinetic and Pharmacodynamic Assessment of Oral Valganciclovir in the Treatment of Symptomatic Congenital Cytomegalovirus Disease. David W Kimberlin,.
    academic.oup.com/jid/article/197/6/836/919779
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